Monoclonal Antibody to TLR2 (Clone: ABM3A87)
TLR2 (Toll-Like Receptors 2) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 also interacts with a large number of non-TLR molecules, allowing for recognition of a great number and variety of PAMPs (pathogen-associated molecular patterns) . TLR2 expression has been detected in immune cells, endothelial, and epithelial cells.
Product Specifications
Product Name Alternative
TLR2||TIL4
Gene Name
TLR2
Gene ID
7097
UniProt
O60603
Host
Mouse
Reactivity
Mouse, Human
Immunogen
A partial length recombinant TLR2 protein (amino acids 180-420) was used as the immunogen for this antibody.
Target Antigen
TLR2
Clonality
Monoclonal
Clone
ABM3A87
Applications
IHC, FACS, WB, IF
Purification
Protein G Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL, FACS analysis: 0.5 μg/10^6 cells, Immunohistochemical analysis: 5 μg/mL
Isotype
Mouse IgG1 Kappa
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