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NALETM Monoclonal Antibody to TLR8/CD288 (Clone: ABM15F6)

Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.

Product Specifications

Product Name Alternative

TLR8||UNQ249/PRO286

Gene Name

TLR8

Gene ID

51311

UniProt

Q9NR97

Host

Mouse

Reactivity

Human

Immunogen

A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody.

Target Antigen

TLR8/CD288

Clonality

Monoclonal

Clone

ABM15F6

Applications

IHC, FACS

Purification

Protein G Chromatography

Format

Azide Free, Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Immunohistochemical analysis: 5 μg/mL; FACS analysis: 2 μg/10^6 cells

Isotype

Mouse IgG1 Kappa

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