Recombinant Human PD-1 rabbit monoclonal Antibody (Clone: ABMRR01)
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
Product Specifications
Product Name Alternative
PDCD1, PD1, CD279
Gene Name
PDCD1
Gene ID
5133
UniProt
Q15116
Host
Recombinant
Reactivity
Human
Target Antigen
PD-1
Clonality
Monoclonal
Clone
ABMRR01
Applications
FACS, WB
Purification
Protein A Chromatography
Format
Purified
Components
100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
FACS: 0.5-1 μg/10^6, WB: 1-2 μg/mL
Isotype
Rabbit IgG
Frequently Asked Questions
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