Nav1.7-IN-15
Nav1.7-IN-15 (Compd 9) is a potent and state-dependent Nav1.7 antagonist, with an IC50 of 0.42 μM for hNav1.7 PX[1].
Product Specifications
CAS Number
1356834-62-2
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nav1-7-in-15.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)C(SCC2=CC=C(C(C)(C)C)C=C2)=NC(N)=C1
Molecular Formula
C16H21N3OS
Molecular Weight
303.42
References & Citations
[1]Hanh Nho Nguyen, et al. Discovery and optimization of aminopyrimidinones as potent and state-dependent Nav1.7 antagonists. Bioorg Med Chem Lett. 2012 Jan 15;22 (2) :1055-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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