(-)-Fucose
Product Specifications
UNSPSC Description
(-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth[2].
Target Antigen
Endogenous Metabolite; Parasite
Type
Natural Products
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/_-_-Fucose.html
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
O=C[C@H]([C@@H]([C@@H]([C@H](C)O)O)O)O
Molecular Weight
164.16
References & Citations
[1]Becker DJ, et al. Fucose: biosynthesis and biological function in mammals. Glycobiology. 2003 Jul;13(7):41R-53R.|[2]Howard MC, et al., l-Fucose prevention of renal ischaemia/reperfusion injury in Mice. FASEB J. 2020 Jan;34(1):822-834.|[3]Tomsik, P, et al.,L-rhamnose and L-fucose suppress cancer growth in mice.cent.eur.j.biol.6, 1–9 (2011).
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N1480/minus-Fucose-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N1480/minus-Fucose-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
2438-80-4
Available Sizes
Curated Selection
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