(-) -Fucose

(-) -Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-) -Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth[2].

Product Specifications

CAS Number

[2438-80-4]

Product Name Alternative

6-Desoxygalactose; L- (-) -Fucose; L-Galactomethylose

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection; Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/_-_-Fucose.html

Concentration

10mM

Purity

99.0

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C[C@H]([C@@H]([C@@H]([C@H](C)O)O)O)O

Molecular Formula

C6H12O5

Molecular Weight

164.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Becker DJ, et al. Fucose: biosynthesis and biological function in mammals. Glycobiology. 2003 Jul;13 (7) :41R-53R.|[2]Howard MC, et al., l-Fucose prevention of renal ischaemia/reperfusion injury in Mice. FASEB J. 2020 Jan;34 (1) :822-834.|[3]Tomsik, P, et al., L-rhamnose and L-fucose suppress cancer growth in mice.cent.eur.j.biol.6, 1–9 (2011) .