CAQK peptide

CAQK peptide selectively binds to injured mouse brain. CAQK peptide selectively targets demyelinating areas and it is absent from healthy tissue. The CAQK peptide target is a proteoglycan complex upregulated in brain injuries and is used for drug delivery. CAQK peptide can penetrate the blood-brain barrier[1][2].

Product Specifications

CAS Number

[2088281-24-5]

UNSPSC

12352209

Target

Biochemical Assay Reagents

Type

Peptides

Related Pathways

Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/caqk-peptide.html

Purity

95.10

Solubility

DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL

Smiles

O=C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(O)=O)=O)=O)[C@H](CS)N

Molecular Formula

C17H32N6O6S

Molecular Weight

448.54

References & Citations

[1]Charly Abi-Ghanem, et al. CAQK, a peptide associating with extracellular matrix components targets sites of demyelinating injuries. Front Cell Neurosci. 2022 Aug 22:16:908401.|[2]Aman P Mann, et al. A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries. Nat Commun. 2016 Jun 28:7:11980.