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CleanCap OVA mRNA, 1 mg

Ovalbumin (OVA) is a member of the serpin superfamily and the predominant glycoprotein found in egg whites. It is a commonly used antigen for immunization and biochemical studies and is an established model allergen for airway hyper-responsiveness. This mRNA is capped usingCleanCap® Reagent AG, TriLink's patented co-transciptional capping technology, which results in the naturally occurring Cap-1 structure with >95% capping efficiency. It is manufactured using TriLink'sCleanScriptTM method*, polyadenylated, and optimized for mammalian systems. It mimics a fully processed mature mRNA. CleanCap® Reagent AG produces a base-modified Cap-1 mRNA, which shows superiorin vivoactivity compared to Cap-0 mRNA produced by legacy capping methods such as mCap or anti-reverse cap analog (ARCA) . CleanScriptTM method is TriLink's proprietaryin vitrotranscription process that is optimized to minimize dsRNA formation and increase mRNA activityinvivo. *Starting April 30th, 2024

Product Specifications

Applications

Immunotherapeutics

Concentration

1.0 mg/mL

Purity

Passes Agarose Gel Mobility

Length

1438 nucleotides

Buffer

1 mM Sodium Citrate pH 6.4

Components

Unmodified bases

Shipping Conditions

Frozen

Storage Conditions

At or below -40°C

Applications Notes

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.

Brand

CleanCap

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