CleanCap OVA mRNA, 100 ug
Ovalbumin (OVA) is a member of the serpin superfamily and the predominant glycoprotein found in egg whites. It is a commonly used antigen for immunization and biochemical studies and is an established model allergen for airway hyper-responsiveness. This mRNA is capped usingCleanCap® Reagent AG, TriLink's patented co-transciptional capping technology, which results in the naturally occurring Cap-1 structure with >95% capping efficiency. It is manufactured using TriLink'sCleanScriptTM method*, polyadenylated, and optimized for mammalian systems. It mimics a fully processed mature mRNA. CleanCap® Reagent AG produces a base-modified Cap-1 mRNA, which shows superiorin vivoactivity compared to Cap-0 mRNA produced by legacy capping methods such as mCap or anti-reverse cap analog (ARCA) . CleanScriptTM method is TriLink's proprietaryin vitrotranscription process that is optimized to minimize dsRNA formation and increase mRNA activityinvivo. *Starting April 30th, 2024
Product Specifications
Applications
Immunotherapeutics
Concentration
1.0 mg/mL
Purity
Passes Agarose Gel Mobility
Length
1438 nucleotides
Buffer
1 mM Sodium Citrate pH 6.4
Components
Unmodified bases
Shipping Conditions
Frozen
Storage Conditions
At or below -40°C
Applications Notes
Brand
CleanCap
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