CleanCap Reagent AU, 100 μmole

TriLink's patented CleanCap® Reagent AU is designed for the co-transcriptional capping of mRNA to produce an mRNA with naturally occurring Cap 1. CleanCap Reagent AU was specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN) . The positive sense strand genomes of these viruses start with a 5' AU structure. Cap 1 mRNAs have superior in vivo activity compared to Cap 0 mRNA produced by legacy co-transcriptional capping methods like anti-reverse cap analog (ARCA) . PLEASE NOTE: CleanCap Reagent AU requires an AU initiator. To learn more, please review the Product Insert below. TriLink's patented CleanCap reagents are available in "Research Use" grade as well as GMP-grade "For Further Processing." GMP product is manufactured in accordance with ISO 9001:2015 and Quality Standards as defined in a GMP Quality Agreement. To learn more visit:

Product Specifications

Applications

CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases

Concentration

100 mM

Purity

≥95% by AX-HPLC

Form

Na+

Buffer

H2O

Molecular Formula

C31H42N12O25P4 (free acid)

Molecular Weight

1106.6 g/mole (free acid)

Shipping Conditions

Frozen

Storage Conditions

-20°C or below

Applications Notes

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.