CleanCap Reagent AU, 5 umole

TriLink's patented CleanCap® Reagent AU is designed for the co-transcriptional capping of mRNA to produce an mRNA with naturally occurring Cap 1. CleanCap Reagent AU was specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN) . The positive sense strand genomes of these viruses start with a 5' AU structure. Cap 1 mRNAs have superior in vivo activity compared to Cap 0 mRNA produced by legacy co-transcriptional capping methods like anti-reverse cap analog (ARCA) . PLEASE NOTE: CleanCap Reagent AU requires an AU initiator. To learn more, please review the Product Insert below. TriLink's patented CleanCap reagents are available in "Research Use" grade as well as GMP-grade "For Further Processing." GMP product is manufactured in accordance with ISO 9001:2015 and Quality Standards as defined in a GMP Quality Agreement. To learn more visit: