7-Deaza-2'-deoxyguanosine-5'-Triphosphate, 5 umoles

This deoxyguanosine analog lacks the N7 nitrogen found in the natural guanine nucleobase. Replacement of this nitrogen atom with a carbon atom results in diminished structure of the major groove in DNA and may disrupt base stacking, but does not interfere with Watson-Crick base pairing. This is desirable for applications such as amplification and sequencing of GC-rich nucleic acid sequences.

Product Specifications

Applications

Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies

Concentration

100 mM

Purity

≥95% by AX-HPLC

Form

Li+

Buffer

H2O

Molecular Formula

C11H17 N4O13P3 (free acid)

Molecular Weight

506.00 g/mole (free acid)

Shipping Conditions

Frozen

Storage Conditions

-20°C or below

Applications Notes

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.