6-Thio-2'-deoxyguanosine-5'-Triphosphate

The nucleoside analogue 6-thio-2’-deoxyguanosine (6-thio-dG) is a substrate for telomerase and is incorporated into de novo synthesized telomeres. This results in modified telomeres, leading to telomere dysfunction in cells expressing telomerase, such as cancer cells.

Product Specifications

Applications

Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies

Concentration

100 mM

Purity

≥90% by AX-HPLC

Form

Li+

Buffer

H2O

Molecular Formula

C10H16N5O12P3S (free acid)

Molecular Weight

523.20 g/mole (free acid)

Shipping Conditions

Frozen

Storage Conditions

-20°C or below

Applications Notes

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.