6-Thio-2'-deoxyguanosine-5'-Triphosphate
The nucleoside analogue 6-thio-2’-deoxyguanosine (6-thio-dG) is a substrate for telomerase and is incorporated into de novo synthesized telomeres. This results in modified telomeres, leading to telomere dysfunction in cells expressing telomerase, such as cancer cells.
Product Specifications
Applications
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Concentration
100 mM
Purity
≥90% by AX-HPLC
Form
Li+
Buffer
H2O
Molecular Formula
C10H16N5O12P3S (free acid)
Molecular Weight
523.20 g/mole (free acid)
Shipping Conditions
Frozen
Storage Conditions
-20°C or below
Applications Notes
Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.
Product Name Synonym
5'-Triphosphate
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