5-Hydroxymethyl-2'-deoxycytidine-5'-Triphosphate
Methylated deoxycytidine analogs are well studied epigenetic modifications. 5-Hydroxymethyl-2'-deoxycytidine has recently been discovered in mammalian genomic DNA, but is substantially depleted in many types of human cancers. A strong inverse relationship has been demonstrated between the proliferation rate of cells and the global level of 5-hydroxymethyl-2'-deoxycytidine in both porcine and rat tissues, but no such relationship was observed for 5-formyl-2'-deoxycytidine and 5-carboxyl-2'-deoxycytidine.
Product Specifications
Applications
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Concentration
100 mM
Purity
≥90% by AX-HPLC
Form
Li+
Buffer
H2O
Molecular Formula
C10H18N3O14P3 (free acid)
Molecular Weight
497.10 g/mole (free acid)
Shipping Conditions
Frozen
Storage Conditions
-20°C or below
Applications Notes
Product Name Synonym
5'-Triphosphate
Frequently Asked Questions
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