BAM7
BAM7 is a direct and selective activator of proapoptotic BAX with an IC50 of 3.3 μM.
Product Specifications
CAS Number
331244-89-4
UNSPSC
12352005
Hazard Statement
H302
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bam7.html
Purity
98.53
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
CCOC1=CC=CC=C1N/N=C2C(C)=NN(C3=NC(C4=CC=CC=C4)=CS3)C\2=O
Molecular Formula
C21H19N5O2S
Molecular Weight
405.47
Precautions
H302
References & Citations
[1]Gavathiotis E, et al. Direct and selective small-molecule activation of proapoptotic BAX. Nat Chem Biol. 2012 Jul;8 (7) :639-45.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax
Available Sizes
Frequently Asked Questions
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