BAM7

BAM7 is a direct and selective activator of proapoptotic BAX with an IC50 of 3.3 μM.

Product Specifications

CAS Number

[331244-89-4]

UNSPSC

12352005

Hazard Statement

H302

Target

Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bam7.html

Purity

98.53

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

CCOC1=CC=CC=C1N/N=C2C(C)=NN(C3=NC(C4=CC=CC=C4)=CS3)C\2=O

Molecular Formula

C21H19N5O2S

Molecular Weight

405.47

Precautions

H302

References & Citations

[1]Gavathiotis E, et al. Direct and selective small-molecule activation of proapoptotic BAX. Nat Chem Biol. 2012 Jul;8 (7) :639-45.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Bax

Available Sizes

Curated Selection

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