2,2′-Dihydroxy-6,6′-dinaphthyl disulfide
2,2′-Dihydroxy-6,6′-dinaphthyl disulfide (PIR-3.5) is a PAK1 inhibitor[1].
Product Specifications
CAS Number
[6088-51-3]
Product Name Alternative
DDD; Bis (6-hydroxy-2-naphthyl) disulfide; PIR-3.5
UNSPSC
12352005
Hazard Statement
H315, H319
Target
PAK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-2-dihydroxy-6-6-dinaphthyl-disulfide.html
Purity
98.49
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C(C=C2)=C1)C=C2SSC3=CC4=CC=C(O)C=C4C=C3
Molecular Formula
C20H14O2S2
Molecular Weight
350.45
Precautions
H315, H319
References & Citations
[1]Flaiz C, et al. PAK kinase regulates Rac GTPase and is a potential target in human schwannomas. Exp Neurol. 2009;218 (1) :137-144.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Isoform
PAK1
Available Sizes
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