Rhapontin (Standard)
Rhapontin (Standard) is the analytical standard of Rhapontin. This product is intended for research and analytical applications. Rhapontin (Rhaponiticin) is an orally aactive SIRT1 agonist and AMPK activator with anti-inflammatory and anti-fibrotic activities. Rhapontin inhibits NLRP3 inflammasome activation by activating SIRT1 and inhibits TGF-β/Smad signaling via the AMPK pathway. Rhapontin reduces intestinal and lung inflammation, inhibits fibroblast differentiation and extracellular matrix deposition, and enhances tight junction protein expression to repair epithelial barriers. Rhapontin can be used in the study of inflammatory bowel diseases (such as ulcerative colitis) and pulmonary fibrosis[1][2][3].
Product Specifications
CAS Number
155-58-8
Product Name Alternative
Rhaponiticin (Standard)
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Apoptosis; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Others
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rhapontin-standard.html
Purity
99.79
Smiles
O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC2=CC(/C=C/C3=CC(O)=C(OC)C=C3)=CC(O)=C2
Molecular Formula
C21H24O9
Molecular Weight
420.41
Precautions
H302, H312, H332
References & Citations
Rheum officinale Baillon
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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