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(R) -Exatecan Intermediate 1

(R) -Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1. Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2].

Product Specifications

CAS Number

110351-91-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

ADC Payload; Topoisomerase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-exatecan-intermediate-1.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1[C@@](O)(CC)C(C=C23)=C(CO1)C(N3CCC2=O)=O

Molecular Formula

C13H13NO5

Molecular Weight

263.25

Precautions

H302, H315, H319, H335

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Camptothecins

Available Sizes

Frequently Asked Questions

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