(R) -Exatecan Intermediate 1
(R) -Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487) . Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2].
Product Specifications
CAS Number
[110351-91-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-exatecan-intermediate-1.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1[C@@](O)(CC)C(C=C23)=C(CO1)C(N3CCC2=O)=O
Molecular Formula
C13H13NO5
Molecular Weight
263.25
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
CD62E (LECAM, E-Selectin, Endothelial Leukocyte Adhesion Molecule, CD62 Antigen-like Family Member E, Endothelial Leukocyte Adhesion Molecule 1, ELAM-1, Leukocyte-endothelial Cell Adhesion Molecule 2, LECAM2, SELE, ELAM1) (AP)
CD62E (LECAM, E-Selectin, Endothelial Leukocyte Adhesion Molecule, CD62 Antigen-like Family Member E, Endothelial Leukocyte Adhesion Molecule 1, ELAM-1, Leukocyte-endothelial Cell Adhesion Molecule 2, LECAM2, SELE, ELAM1) (AP)
