CYP51-IN-12

CYP51-IN-2 (compound 1l), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80 of 15.6 ng/mL for Microsporum gypseum and Candida albicans[1].

Product Specifications

CAS Number

[1155361-10-6]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyp51-in-12.html

Smiles

OC(CN(CC1=CC=C([N+]([O-])=O)C=C1)CC=C)(C2=CC=C(F)C=C2F)CN3N=CN=C3

Molecular Formula

C21H21F2N5O3

Molecular Weight

429.42

References & Citations

[1]Chai X, et, al. Design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase. Eur J Med Chem. 2009 May;44 (5) :1913-20.