Vimnerixin
Vimnerixin (AZD4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 (CXCR2) . Vimnerixin has the potential for the research of inflammatory disease[1].
Product Specifications
CAS Number
[1418112-77-2]
Product Name Alternative
AZD4721; RIST4721
UNSPSC
12352005
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vimnerixin.html
Purity
99.16
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(NC1=NC(SCC2=CC=C(C=C2)F)=NC(O[C@H](C)[C@@H](O)CO)=C1)(N3CC(C3)C)=O
Molecular Formula
C19H25FN4O5S2
Molecular Weight
472.55
References & Citations
[1]Gardiner P, et al. Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs. Drug Metab Dispos. 2019;47 (8) :865-873.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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