5-Methylfurfural

5-Methylfurfural is a chemical that can be utilized as food additive, intermediate in the production of agrochemicals, and precursor of certain anti-cancer natural products. 5-Methylfurfural is formed during the photoexposition of ranitidine hydrochloride. 5-Methylfurfural is an organic compound. 5-Methylfurfural has a strong tendency to be further hydrogenated to 2,5-dimethylfuran (DMF) . 5-Methylfurfural can predominantly evoke skin inflammation and barrier disintegration. 5-Methylfurfural degrades native DNA through the formation of single-strand breaks[1][2][3][4][5].

Product Specifications

CAS Number

[620-02-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; COX

Type

Natural Products

Related Pathways

Immunology/Inflammation; Others

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/5-Methylfurfural.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=CC1=CC=C(C)O1

Molecular Formula

C6H6O2

Molecular Weight

110.11

Precautions

H302, H315, H319, H335

References & Citations

[1]Lin Dong, et al., Selective hydrogenolysis of 5-hydroxymethylfurfural to 5-methylfurfural over Au/TiO2, Applied Catalysis B: Environmental, Volume 335, 2023, 122893, ISSN 0926-3373. |[2]Marzena Jamrógiewicz, et al., Detection of some volatile degradation products released during photoexposition of ranitidine in a solid state, Journal of Pharmaceutical and Biomedical Analysis, Volume 76, 2013, Pages 177-182, ISSN 0731-7085. |[3]Li, S., et al., (2021) . Selective hydrogenation of 5- (hydroxymethyl) furfural to 5-methylfurfural over single atomic metals anchored on Nb2O5. Nature communications, 12 (1), 584.|[4]Lin, Y. K., et al., (2024) . Systematic establishment of the relationship between skin absorption and toxicity of furanoids via in silico, in vitro, and in vivo assessments. Environmental research, 261, 119757.|[5]Shahabuddin, Rahman, A., & Hadi, S. M. (1990) . Specificity of the in vitro interaction of methylfurfural with DNA. Mutagenesis, 5 (2), 131–136.