2-O-Methylcytosine

2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase[1].

Product Specifications

CAS Number

[3289-47-2]

UNSPSC

12352005

Hazard Statement

H302, H319

Target

DNA/RNA Synthesis; Endogenous Metabolite

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-o-methylcytosine.html

Concentration

10mM

Purity

99.97

Solubility

DMSO : 60 mg/mL (ultrasonic)

Smiles

NC1=NC(OC)=NC=C1

Molecular Formula

C5H7N3O

Molecular Weight

125.13

Precautions

H302, H319

References & Citations

[1]Aliakbar Tehrani Z, et al. Comparison of gas phase intrinsic properties of cytosine and thymine nucleobases with their O-alkyl adducts: different hydrogen bonding preferences for thymine versus O-alkyl thymine. J Mol Model. 2013;19 (8) :2993‐3005.