Anti-Hu CD303 Alexa Fluor® 488
CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
CD303 ectodomain fused with human IgG Fc domain
Target Antigen
CD303
Clone
15E3
Applications
ICC, FC, IHC-F
Format
Alexa Fluor® 488
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Isotype
Mouse IgG1 kappa
Frequently Asked Questions
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