Recombinant Human PD-L1/B7-H1 Protein

<strong>Recombinant Human PD-L1/B7-H1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2019261_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 25.2 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> B7-H Protein, Human; B7-H1 Protein, Human; B7H1 Protein, Human; hPD-L1 Protein, Human; PD-L1 Protein, Human; PDCD1L1 Protein, Human; PDCD1LG1 Protein, Human; PDL1 Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Harshman LC, Choueiri TK, Drake C, Stephen Hodi F Jr. Subverting the B7-H1/PD-1 pathway in advanced melanoma and kidney cancer Cancer J. 2014 Jul-Aug;20(4):272-80._x000D_ 2: Jeon S, St Leger AJ, Cherpes TL, Sheridan BS, Hendricks RL. PD-L1/B7-H1 regulates the survival but not the function of CD8+ T cells in herpes simplex virus type 1 latently infected trigeminal ganglia J Immunol. 2013 Jun 15;190(12):6277-86._x000D_ 3: Eckel-Passow JE, Ho TH, Serie DJ, Cheville JC, Houston Thompson R, Costello BA, Dong H, Kwon ED, Leibovich BC, Parker AS. Concordance of PD-1 and PD-L1 (B7-H1) in paired primary and metastatic clear cell renal cell carcinoma Cancer Med. 2020 Feb;9(3):1152-1160._x000D_ 4: Inman BA, Sebo TJ, Frigola X, Dong H, Bergstralh EJ, Frank I, Fradet Y, Lacombe L, Kwon ED. PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression Cancer. 2007 Apr 15;109(8):1499-505._x000D_ 5: Chauhan P, Lokensgard JR. Glial Cell Expression of PD-L1 Int J Mol Sci. 2019 Apr 4;20(7):1677._x000D_ 6: Krönig H, Kremmler L, Haller B, Englert C, Peschel C, Andreesen R, Blank CU. Interferon-induced programmed death-ligand 1 (PD-L1/B7-H1) expression increases on human acute myeloid leukemia blast cells during treatment Eur J Haematol. 2014 Mar;92(3):195-203._x000D_ 7: Sumpter TL, Thomson AW. The STATus of PD-L1 (B7-H1) on tolerogenic APCs Eur J Immunol. 2011 Feb;41(2):286-90._x000D_ 8: Lipson EJ, Forde PM, Hammers HJ, Emens LA, Taube JM, Topalian SL. Antagonists of PD-1 and PD-L1 in Cancer Treatment Semin Oncol. 2015 Aug;42(4):587-600._x000D_ 9: Planès R, BenMohamed L, Leghmari K, Delobel P, Izopet J, Bahraoui E. HIV-1 Tat protein induces PD-L1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha- and toll-like receptor 4-mediated mechanisms J Virol. 2014 Jun;88(12):6672-89._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30236481">10: León-Flores A, Del Río Estrada PM, Álvarez-García LX, Piten-Isidro E, Reyes-Terán G. Increased levels of soluble co-stimulatory molecule PD-L1 (B7-H1) in the plasma of viraemic HIV-1(+) individuals Immunol Lett. 2018 Nov;203:70-79. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human PD-L1/B7-H1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>