Cecropin P1, porcine

Cecropin P1, porcine is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine shows antiviral activity and inhibits PRRSV infection[1][2].

Product Specifications

CAS Number

[125667-96-1]

UNSPSC

12352209

Target

Bacterial; Endogenous Metabolite

Type

Peptides

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cecropin-p1-porcine.html

Purity

99.83

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(NCC(NCC(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N

Molecular Formula

C147H253N45O43

Molecular Weight

3338.86

References & Citations

[1]Andersson M, et al. Ascaris nematodes from pig and human make three antibacterial peptides: isolation of cecropin P1 and two ASABF peptides. Cell Mol Life Sci. 2003 Mar;60 (3) :599-606. |[2]Guo C, et al. Cecropin P1 inhibits porcine reproductive and respiratory syndrome virus by blocking attachment. BMC Microbiol. 2014 Nov 18;14:273.|[3]Giacometti A, et al. Effect of mono-dose intraperitoneal cecropins in experimental septic shock. Crit Care Med. 2001 Sep;29 (9) :1666-9. |[4]Jiang R, et al. Expression of antimicrobial peptide Cecropin P1 in Saccharomyces cerevisiae and its antibacterial, antiviral activity in vitro. Electronic Journal of Biotechnology, 2020.