Lurtotecan (dihydrochloride)

Lurtotecan dihydrochloride (GI147211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan dihydrochloride has anticancer effects[1].

Product Specifications

CAS Number

[155773-58-3]

Product Name Alternative

GI147211 (dihydrochloride) ; OSI-211 (dihydrochloride)

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lurtotecan-dihydrochloride.html

Smiles

O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CN5CCN(C)CC5)C6=CC(OCCO7)=C7C=C6N=C4C3=C2)=O.Cl.Cl

Molecular Formula

C28H32Cl2N4O6

Molecular Weight

591.48

References & Citations

[1]D L Emerson, et al. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res. 1995 Feb 1;55 (3) :603-9.