Lurtotecan (dihydrochloride)
Lurtotecan dihydrochloride (GI147211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan dihydrochloride has anticancer effects[1].
Product Specifications
CAS Number
[155773-58-3]
Product Name Alternative
GI147211 (dihydrochloride) ; OSI-211 (dihydrochloride)
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lurtotecan-dihydrochloride.html
Smiles
O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CN5CCN(C)CC5)C6=CC(OCCO7)=C7C=C6N=C4C3=C2)=O.Cl.Cl
Molecular Formula
C28H32Cl2N4O6
Molecular Weight
591.48
References & Citations
[1]D L Emerson, et al. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res. 1995 Feb 1;55 (3) :603-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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