Recombinant Kex2 Protease, Expressed in Yeast, GMP grade

Kex2 protease, also known as a double-alkaline endopeptidase or YSCF protease, is a calcium-dependent serine protease that is responsible for processing the precursors of killer toxin and α-factor within yeast cells. It specifically recognizes and cleaves the peptide bonds at the carboxyl end of dibasic amino acids such as Arg-Arg and Lys-Arg. Unlike trypsin, Kex2 does not recognize and cleave the peptide bonds at the carboxyl end of single basic amino acids, such as arginine or lysine. The activity of Kex2 protease is not inhibited by conventional serine protease inhibitors such as aprotinin, PMSF, or TPCK.