Nociceptin (1-7)
Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183) . Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo[1].
Product Specifications
CAS Number
[178249-42-8]
UNSPSC
12352209
Target
Opioid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nociceptin-1-7.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](C(O)=O)NC(CNC([C@H]([C@H](O)C)NC([C@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC2=CC=CC=C2)N)=O)=O)=O)=O)=O)=O
Molecular Formula
C31H41N7O9
Molecular Weight
655.70
References & Citations
[1]T Sakurada, et al. Nociceptin (1 - 7) antagonizes nociceptin-induced hyperalgesia in mice.Br J Pharmacol. 1999 Nov;128 (5) :941-4.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NOP Receptor/ORL1
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