S7A14 rabbit pAb
This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014],
Product Specifications
Background
Synonyms
Probable cationic amino acid transporter (Solute carrier family 7 member 14)
Gene ID
57709
UniProt
Q8TBB6
Cellular Locus
Lysosome membrane ; Multi-pass membrane protein. Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human S7A14 AA range: 50-100
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000
Molecular Weight
85kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES13220-1.pdf
Observed Molecular Weight
85 kD
Subcellular Location
Lysosome membrane ; Multi-pass membrane protein . Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes.
Other Product Names
Probable cationic amino acid transporter (Solute carrier family 7 member 14)
Gene ID (Human)
57709
SwissProt (Human)
Q8TBB6
Available Sizes
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