BAY 1003803
BAY 1003803 is a glucocorticoid receptor agonist for the topical research of psoriasis or severe atopic dermatitis.
Product Specifications
CAS Number
[1152781-51-5]
UNSPSC
12352005
Hazard Statement
H361, H372
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bay-1003803.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=CC(N[C@@H](C2=C(C(F)=C(C=C2)OC)Cl)[C@](C(F)(F)F)(O)COC)=C3C(NC(C=C3)=O)=C1
Molecular Formula
C21H18ClF5N2O4
Molecular Weight
492.82
Precautions
H361, H372
References & Citations
[1]Berger M, et al. Discovery of the potent non-steroidal glucocorticoid receptor modulator BAY 1003803 as clinical candidate. Bioorg Med Chem Lett. 2020 Aug 15;30 (16) :127298.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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