N-Methylisatoic anhydride

N-Methylisatoic anhydride is a heteronucleoside anhydride derivative conjugated with biotin and a disulfide linker for specific 2'-OH acylation of RNA. Biotin-conjugated N-Methylisatoic anhydride can selectively capture RNA from a mixture of biological RNA and DNA[1].

Product Specifications

CAS Number

[10328-92-4]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-methylisatoic-anhydride.html

Purity

99.94

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(OC1=O)N(C)C2=C1C=CC=C2

Molecular Formula

C9H7NO3

Molecular Weight

177.16

Precautions

H315, H319, H335

References & Citations

[1]Ursuegui S, et al. Biotin-conjugated N-methylisatoic anhydride: a chemical tool for nucleic acid separation by selective 2'-hydroxyl acylation of RNA. Chem Commun (Camb) . 2014 Jun 1;50 (43) :5748-51.