Dithranol (Standard)
Product Specifications
UNSPSC Description
Dithranol (Standard) is the analytical standard of Dithranol. This product is intended for research and analytical applications. Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair[1][2].
Target Antigen
DNA/RNA Synthesis
Type
Reference Standards
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dithranol-standard.html
Smiles
O=C1C2=C(C=CC=C2O)CC3=CC=CC(O)=C13
Molecular Weight
226.23
References & Citations
[1]L Kemény , et al. Dithranol: a review of the mechanism of action in the treatment of psoriasis vulgaris. Skin Pharmacol. 1990;3(1):1-20.|[2]J M Clark, et al. Inhibition of DNA replication and repair by anthralin or danthron in cultured human cells. J Invest Dermatol. 1982 Jul;79(1):18-22.|[3]A Farkas, et al. Dithranol upregulates IL-10 receptors on the cultured human keratinocyte cell line HaCaT. Inflamm Res. 2001 Jan;50(1):44-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0738R/Dithranol-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0738R/
CAS Number
1143-38-0
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495250 6 Bottles x 400 mL (Capacity 500 mL)
Physiological Solution (Perforable) (Culture media in glass tubes/bottles)
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