Dithranol (Standard)
Dithranol (Standard) is the analytical standard of Dithranol. This product is intended for research and analytical applications. Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair[1][2].
Product Specifications
CAS Number
1143-38-0
Product Name Alternative
Anthralin (Standard)
UNSPSC
12352005
Target
DNA/RNA Synthesis; Reference Standards
Type
Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dithranol-standard.html
Smiles
O=C1C2=C(C=CC=C2O)CC3=CC=CC(O)=C13
Molecular Formula
C14H10O3
Molecular Weight
226.23
References & Citations
[1]L Kemény , et al. Dithranol: a review of the mechanism of action in the treatment of psoriasis vulgaris. Skin Pharmacol. 1990;3 (1) :1-20.|[2]J M Clark, et al. Inhibition of DNA replication and repair by anthralin or danthron in cultured human cells. J Invest Dermatol. 1982 Jul;79 (1) :18-22.|[3]A Farkas, et al. Dithranol upregulates IL-10 receptors on the cultured human keratinocyte cell line HaCaT. Inflamm Res. 2001 Jan;50 (1) :44-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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