IXA6
IXA6 is a novel IRE1/XBP1s activator, and can induce IRE1 RNase activity[1].
Product Specifications
CAS Number
[1021106-40-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IRE1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ixa6.html
Purity
99.29
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
O=C(CN(S(=O)(C1=CC=CN=C1)=O)CC2=CC=C(C=C2)Cl)N3C4=C(CC3)C=CC=C4
Molecular Formula
C22H20ClN3O3S
Molecular Weight
441.94
Precautions
H302, H315, H319, H335
References & Citations
[1]Julia M D Grandjean, et al. Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nat Chem Biol. 2020 Oct;16 (10) :1052-1061.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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