IXA6

IXA6 is a novel IRE1/XBP1s activator, and can induce IRE1 RNase activity[1].

Product Specifications

CAS Number

[1021106-40-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IRE1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ixa6.html

Purity

99.29

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

O=C(CN(S(=O)(C1=CC=CN=C1)=O)CC2=CC=C(C=C2)Cl)N3C4=C(CC3)C=CC=C4

Molecular Formula

C22H20ClN3O3S

Molecular Weight

441.94

Precautions

H302, H315, H319, H335

References & Citations

[1]Julia M D Grandjean, et al. Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nat Chem Biol. 2020 Oct;16 (10) :1052-1061.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GW8980-250mg 250 mg

8-Butyryloxy-pyren-1,3,6-trisulfonic acid

Ask

View Details

abx142623-01 100 µL

Mouse Anti-Human IgM Antibody (AF647)

Ask

View Details

abx142623-02 500 µL

Mouse Anti-Human IgM Antibody (AF647)

Ask

View Details

abx142623-03 1 mL

Mouse Anti-Human IgM Antibody (AF647)

Ask

View Details

TA810616S 30 µL

Glutathione Transferase zeta 1 (GSTZ1) Mouse Monoclonal Antibody [Clone ID: OTI6A10]

Ask

View Details

E106764 1 Each

Human MR-ProADM ELISA Kit

Ask

View Details