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IXA6

IXA6 is a novel IRE1/XBP1s activator, and can induce IRE1 RNase activity[1].

Product Specifications

CAS Number

[1021106-40-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IRE1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ixa6.html

Purity

99.29

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

O=C(CN(S(=O)(C1=CC=CN=C1)=O)CC2=CC=C(C=C2)Cl)N3C4=C(CC3)C=CC=C4

Molecular Formula

C22H20ClN3O3S

Molecular Weight

441.94

Precautions

H302, H315, H319, H335

References & Citations

[1]Julia M D Grandjean, et al. Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nat Chem Biol. 2020 Oct;16 (10) :1052-1061.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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