N2-Acetylguanine
N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1].
Product Specifications
CAS Number
19962-37-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis; Endogenous Metabolite
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/n2-acetylguanine.html
Purity
99.92
Solubility
DMSO : 3.57 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C1N=C(NC2=C1NC=N2)NC(C)=O
Molecular Formula
C7H7N5O2
Molecular Weight
193.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Matyjasik MM, et al. High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules. 2020 May 13;25 (10) :2295.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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