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Complement component 1, q subcomponent, alpha polypeptide Adenovirus (Ad-C1q (A) )

The complement component proteins, C3, C4, and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R, and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation, and cellular chemotaxis. Adipsin, also designated complement factor D, is a serine protease that cleaves complement factor B and may be involved in obesity. C1q, together with proenzymes C1r and C1s, yield C1, the first component of the serum complement system.

Product Specifications

Product Name Alternative

Complement component 1, q subcomponent, alpha polypeptide Adenovirus

UNSPSC

41106621

HS Code

3822190000

Type

Pre-Made

Shipping Conditions

Dry Ice

Storage Conditions

-80C

Shelf Life

12 Months

Short Name

Ad-C1q (A)

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV (ubiquitous)

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Ttiter

1x10^10 PFU/ml

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