Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) Adenovirus (Ad-NFKB2)

The NFkB transcription factor is a protein complex consisting of a 65 kDa DNA binding subunit and an associated 50 kDa protein. The 65 kDa subunit, also referred to as RelA, is functionally related to c-Rel p75 and RelB p68. The p50 subunit is derived from the N-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) is derived from the NFkB2/p100 precursor and may act as an alternative to p50 in NFkB heterodimers.