Aurora kinase A Adenovirus (Ad-Aurora-A)
Aurora related kinase-1 (ARK-1, STK15, STK6, Aurora2) and -2 (ARK-2, STK12, Aurora1) are centrosome-associated serine/threonine kinases that regulate centrosome separation, bipolar spindle assembly and chromosome segregation during mitosis. First characterized in human colorectal cancers, ARK-1 and -2 are closely related to Drosophila aurora kinases. ARK-1 protein has elevated expression in colon carcinoma lines (HT-29, SNU-C2B, COLO 205, SW480, 837 and 948) and accumulates during metaphase in HeLa cells. ARK-1 and -2 have unique genetic loci, suggesting that these two kinases, with oncogenic potential, play different roles in cell cycle progression.
Product Specifications
Product Name Alternative
Aurora kinase A Adenovirus
UNSPSC
41106621
HS Code
3822190000
Type
Pre-Made
Shipping Conditions
Dry Ice
Storage Conditions
-80C
Shelf Life
12 Months
Short Name
Ad-Aurora-A
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Ttiter
1x10^10 PFU/ml
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