VEGFC Protein (N-human IgG1-Fc, Mouse, Rat)

Product Specifications

Abbreviation

VEGFC

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

1. Immobilized mouse FLT4-His (Cat:50584-M08H) at 10 μg/mL (100 μL/well) can bind mouse/rat Fc-VEGFC, The EC50 of mouse/rat Fc-VEGFC is 0.41-0.95 μg/mL. 2. Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC) .The ED50 for this effect is typically 70-300 ng/mL.

Function

Ala108-Arg223

Molecular Weight

The recombinant mouse / rat VEGFC/Fc comprises 376 amino acids and has a predicted molecular mass of 41.5 kDa. The apparent molecular mass of the protein is approximately 44 and 34 kDa in SDS-PAGE under reducing conditions.