A-967079
Product Specifications
UNSPSC Description
A-967079 is a selective TRPA1 receptor antagonist with IC50s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS.
Target Antigen
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/A-967079.html
Purity
99.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCC(/C(C)=C/C1=CC=C(F)C=C1)=N\O
Molecular Weight
207.24
References & Citations
[1]McGaraughty S, et al. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. Mol Pain. 2010 Mar 5;6:14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108463/A-967079-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108463/A-967079-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
1170613-55-4
Available Sizes
Curated Selection
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