TREM2 Protein (C-His-AVI, Human)

Product Specifications

Abbreviation

TREM2

Synonyms

PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c

Host

HEK 293

Tag

C-His-AVI

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized TREM-2 / TREM2 Antibody, Mouse MAb (Cat:11084-MM08) at 1 μg/mL (100 μL/well) can bind Human TREM-2 Protein (ECD, His & AVI Tag), Biotinylated (Cat:11084-H49H-B), the EC50 is 16-45ng/mL. 2.Loaded Biotinylated Recombinant Human TREM-2 Protein, ECD, His & AVI Tag (Cat. No. 11084-H49H-B) on SA Biosensor, can bind Recombinant Human Apolipoprotein E/APOE Protein, isoform E3, His & Trx Tag (Cat. No. 10817-H30E) with an affinity constant of 31.900 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met1-Ser174

Molecular Weight

The recombinant human TREM2 consists of 182 amino acids and predicts a molecular mass of 20.69 kDa. It migrates as an approximately 34.12 kDa band in SDS-PAGE under reducing conditions.

Species

Human