TNFRSF1B Protein (C-human IgG1-Fc, Cynomolgus, Rhesus)
Product Specifications
Abbreviation
TNFRSF1B
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
Measured by its ability to inhibit TNFα-mediated cytotoxicity in L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 4-32 ng/mL in the presence of 1 ng/mL of cynoTNFα.
Function
Met1-Asp257
Molecular Weight
The recombinant cynomolgus / rhesus TNFRSF1B is a disulfide-linked homodimer. The reduced monomer comprises 476 amino acids and has a calculated molecular mass of 52.1 KDa.The apparent molecular mass of the protein is approximately 68 KDa respectively in SDS-PAGE.
Species
Cynomolgus, Rhesus
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