TNFRSF17 Protein (C-human IgG1-Fc & His, Mouse)

Product Specifications

Abbreviation

TNFRSF17

Synonyms

BCM, BCMA, Tnfrsf13, Tnfrsf13a, Tnfrsf17

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

1.Measured by its binding ability in a functional ELISA. Immobilized human BAFF (Cat:10056-HNCH) at 10 μg/ml (100 μl/well) can bind mouse BCMA-Fch, The EC50 of mouse BCMA-Fch is 0.02-0.06 μg/mL. 2.Immobilized Anti-BCMA Antibody, Human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Mouse TNFRSF17 / BCMA Protein (His & Fc Tag) (Cat: 50076-M03H), the EC50 is 3-10 ng/mL (QC tested) .

Function

Met1-Thr49

Molecular Weight

The recombinant mouse BCMA/Fc chimera is a disulfide-linked homodimer The reduced monomer consists of 297 amino acids and has a predicted molecular mass of 33.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm BCMA/Fc monomer is approximately 35-48 kDa due to glycosylation.