TNFRSF12A Protein (N-human IgG1-Fc, Human)

Product Specifications

Abbreviation

TNFRSF12A

Synonyms

CD266, FN14, TWEAKR

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Immobilized Cynomolgus mFc-TNFSF12 (Cat:90094-C04H) at 10 μg/ml (100 μl/well) can bind human Fc-TNFRSF12A, The ED50 of human Fc-TNFRSF12A is 0.07-0.15 μg/ml.

Function

Glu28-Trp79

Molecular Weight

The recombinant human TNFRSF12A/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 313 amino acids and has a calculated molecular mass of 34 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhTNFRSF12A/Fc monomer is approximately 37 kDa.