TNFRSF10B Protein (C-human IgG1-Fc & His, Mouse)

Product Specifications

Abbreviation

TNFRSF10B

Synonyms

DR5, KILLER, Ly98, MK, Tnfrsf10b, TRAILR2, TRICK2A, TRICK2B, TRICKB

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Immobilized human TNFSF10 (Cat:10409-HNAE) at 10 μg/ml (100 μl/well) can bind mouse TNFRSF10B-Fch, The EC50 of mouse TNFRSF10B-Fch is 0.07-0.17 μg/ml.

Function

Met1-Ser177

Molecular Weight

The recombinant mouse TNFRSF10B/Fc chimera is a disulfide-linked homodimer. The reduced monomer consists of 373 amino acids and has a calculated molecular mass of 41.8 kDa. As a result of glycosylation, the apparent molecular mass of the TNFRSF10B/Fc monomer is approximately 50-55 kDa in SDS-PAGE under reducing conditions.