TNFRSF10B Protein (C-His-AVI, Human)

Product Specifications

Abbreviation

TNFRSF10B

Synonyms

CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, UNQ160/PRO186, ZTNFR9

Host

HEK 293

Tag

C-His-AVI

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Loaded Biotinylated Recombinant Human DR5/TRAIL R2 Protein, His & AVI Tag (Cat. No. 10465-H49H-B) on SA Biosensor, can bind Recombinant Human TRAIL/TNFSF10 Protein (Cat. No. 10409-HNAE) with an affinity constant of 12.200 pM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Immobilized Recombinant Human TNFSF10 / TRAIL / APO-2L / CD253 Protein (Cat: 10409-HNAE) at 2 μg/mL (100 μL/well) can bind Recombinant Human DR5/TRAIL R2 Protein (His & AVI Tag), Biotinylated (Cat: 10465-H49H-B), the EC50 is 0.5-2.0 ng/mL (QC tested) .

Function

Met1-Glu182

Molecular Weight

The recombinant Human TNFRSF10B consists of 153 amino acids and predicts a molecular mass of 17.54 kDa. It migrates as an approximately 21.65 kDa band in SDS-PAGE under reducing conditions.

Species

Human